Ramipril is a highly lipophilic,
long acting ACE inhibitor. The drug is used for treating blood
pressure and congestive heart failure. It effectively reduces both
supine and standing blood pressure without significant alteration in
the pulse rate.
Brand Name: Altace, Tritace
Iupac Name:(1S,5S,7S)-8-[(2S)-2-[[(1S)-1-ethoxycarbonyl-3-phenyl-propyl]amino]propanoyl]-8-azabicyclo[3.3.0]octane-7-carboxylic
acid
Working
The drug acts by lowering the production of Angiotensin II,
therefore relaxing arterial muscles while at the same time enlarging
the arteries. The process allows the heart to pump blood easier, and
increasing the blood flow due to more blood being pumped into and
through bigger passageways.
Dosage
Hypertension: 2.5 mg/day, Max: 10mg /day.
Cardiac Failure: 1.25mg/day, increased to 2.5 mg once daily,
Max:10mg/day
Contra- Indications: Hypersensitivity, bilateral renal
artery stenosis, pregnancy, lactation.
Side Effects
The drug has certain side effects, that can affect individuals in
different ways. The following are some of the side effects, that are
often associated with the drug:
- Hypotension
- Renal impairment
- Cough
- Hyperkalemia
Disclaimer: The above information is for general
understanding of the visitor. Please consult a registered medical
practitioner before taking the aforesaid medicine.
