A Protease Inhibitor is a type of drug that cripples the enzyme Protease.
An enzyme is a substance that triggers chemical reactions in the body. The
Human Immuno-deficiency Virus (HIV) uses protease in the final stages of its
reproduction (replication) process.
Purpose
The drug is used to treat selected patients with HIV infection. Blocking
protease interferes with HIV reproduction, causing it to make copies of
itself that cannot infect new cells. The drug may improve symptoms and
suppress the infection but does not cure it.
Description
Protease inhibitors are considered one of the most potent medications for
HIV developed so far. This class of drugs includes Indinavir (Crixivan),
Ritonavir (Norvir), Nelfinavir (Viracept) and Saquinavir (Invirase or
Fortovase). Several weeks or months of drug therapy may be required before
the full benefits are apparent.
The drug should be taken at the same time each day. Some types should be
taken with a meal to help the body absorb them. Each of the types of
protease inhibitor may have to be taken in a different way.