Nimesulide is a popular NSAID and
available in various forms including tablets, suppositories, water-soluble
powders, and topical gels.
It is an analgesic and antipyretic in action, apart from its anti
inflammatory action. Unlike, other NSAIDs, the chemical structure of
nimesulide does not contain a carboxylic group but a sulfonanilide moiety as
the acidic group. It is absorbed rapidly and completely after oral
administration.
Brand Name: Ainex, Aulin, Donulide, Edrigyl, Eskaflam, Heugan,
Lusemin
Working
It acts by inhibiting the release of tumour necrosis factor-alpha, acts as
a competitive inhibitor of histamine release and reduces superoxide anion
formation
Dosage
Adults: 100 mg twice daily
Children: 5mg/kg of body weight in 2 or 3 divided doses.
Contra- Indications: Hypersensitivity, active peptic ulcer disease,
hepatic impairment
Side Effects
The drug has certain side effects, that can affect individuals in different
ways. The following are some of the side effects, that are often associated
with the drug:
- Diarrhoea
- Vomiting
- Skin rash
- Pruritis
- Dizziness
- Headache
Women should use the drug with caution during lactation and it is
contraindicated during pregnancy.
Disclaimer: The above information is for general understanding
of the visitor. Please consult a registered medical practitioner before
taking the aforesaid medicine.
Injection
Receive QUOTES from Suppliers for FREE