Generic
name: Mesna - injection
Brand name: Mesnex
Description anti cancer medication
Mesna Injection is a detoxing agent to inhibit the hemorrhagic cystitis
induced by ifosfamide. It is a sterile, nonpyrogenic, aqueous solution of
clear and colorless to light pink appearance in clear glass multidose vials
for intravenous administration. Mesna Injection multidose vials also contain
10.4 mg of benzyl alcohol as a preservative. The solution has a pH range of
6.5 to 7.3. It is used to prevent bleeding from the bladder during
ifosfamide or cyclophosphamide chemotherapy.
Appearance
It is sterile, nonpyrogenic, aqueous solution of clear and colorless to
light pink in color.
Uses
- It is used along with ifosfamide or cyclophosphamide to protect
against a bladder condition called hemorrhagic cystitis
- It is used as a prophylactic agent in various medications
- It helps in preventing kidney problems.
How to use \ dosage ?
This medication is administered by injection into a vein by a health care
professional. It is taken for over 15-30 minutes at 4 hours interval . It
must be given along with each ifosfamide dose and drink at least a quart (4
cups) of liquid each day while taking this medication, unless directed
otherwise by your doctor
Safety tips
Tell your doctor your medical history, especially of other illnesses,
allergies. This drug may make you
- Dizzy or drowsy
- Limit alcoholic beverages
- Use caution engaging activities requiring alertness such as driving
or using machinery
- Drink lots of liquids (8-12 cups a day) on the day(s) of your
treatment and the day after your treatment. This helps prevent bladder
and kidney problems.
SEE YOUR DOCTOR OR GET EMERGENCY HELP IMMEDIATELY IF YOU HAVE:
- Skin rash or itching
- Uncontrolled nausea, vomiting or diarrhea
- Signs of bladder problems such as blood in urine, frequent need to
pass urine, pain when you pass urine
NOTE:
It is contraindicated to pregnant and lactating woman. So therefor, caution
is required to prescribe these Patients.
Common side effects
Most side effects are caused not by mesna, but by the chemotherapy or other
medicines taken with mesna. Some of common effects are :
- Bad taste in mouth
- Loss of appetite
- Trouble breathing
- Swelling and rashes
- Flu like symptoms
- Weakness or unusual tiredness
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- Flushing
- Dizziness
- Fever
- Nausea
- Diarrhea
- Vomiting
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Disclaimer:The above information is for general understanding of
the visitor. Please consult a registered medical practitioner before taking
the aforesaid medicine.