Generic
name: Ifosfamide - injection
Brand name: Ifex®
Description
Cancer medication IFOSFAMIDE is a type of chemotherapy for treating
cancer. It is an intravenously administered drug which requires
metabolic activation by microsomal liver enzymes to produce
biologically active metabolites. Urinary metabolites of ifosfamide
are cytotoxic and alkylated metabolites of ifosfamide have been
shown to interact with DNA which result in the formation of DNA-DNA
cross links. It is extensively metabolised in humans and the
metabolic pathway appear to be saturated at high doses. Ifosfamide
is changed by the liver into a substance that interferes with the
growth of rapidly dividing cells, like cancer cells, and eventually
causes these cells to die. Ifosfamide is used in combination with
other chemotherapy agents to treat cancer of the testes and other
cancers. Ifosfamide may also be given as part of regimen prior to
stem cell transplantation.
Uses :
- This injection is often used in combination with other
medications to treat various cancers.
- Helps in reducing kidney and bladder problems.
How to use \ dosage :
This medication is given by a health care professional as an
injection into a vein. It is important to drink large amounts of
fluids while taking this medication. If you have difficulty drinking
large amounts of water, fluid will be given by this medication as
well. It is used for over 30 mins. or more administered
intravenously at a dose of 1.2 gm/m² day for five consecutive
days.
Safety tips
Notify your doctor if you develop any of the following while taking
this medication such as :
- Fever
- Sore throat
- Breathing difficulties
- Unusual bleeding or bruising
- Yellow discoloration of the eyes or skin
- Blood in the urine
- Painful urination
- Severe stomach ache
- Muscle pain.
This Ifosfamide injection affects your blood cells. It is
important to have your blood checked frequently while taking this
medication to monitor the medications effects. If you notice other
effects not listed above, contact your doctor or pharmacist.
Common side effects :
This medication causes
- Diarrhea
- Nausea
- Vomiting
- Constipation
- Hair loss
- Dizziness
|
- Depression
- Muscle ache
- Headache
- Skin rash
- Mouth sores
- Low blood counts
|
Notify your doctor if these symptoms continue or become
bothersome.
Disclaimer: The above information is for general
understanding of the visitor. Please consult a registered medical
practitioner before taking the aforesaid medicine.
