Gliclazide is an anti-diabetic agent
with both metabolic and vascular properties. It restores the early peak of
insulin secretion and ensures glycaemic control throughout 24 hours without
hypoglycaemia.
The drug combats microthrombosis by decreasing platelet hyper adhesiveness &
hyper aggregation, increasing fibrinolytic activity, normalizing
prostaglandin metabolism, scavenging free-radicals.
The drug is also used in combination with a strict diet and exercising
regime for controlling high blood sugar in non-insulin dependent diabetic
patients.
Brand Name: Amaryl, DiaBeta, Diabinese, Dymelor, Glucotrol,
Glucotrol XL
Chemical Description
Dosage
80-320 mg daily. Usually160 mg daily.
Contra- Indications: Pregnancy, Severe renal or hepatic failure,
severe ketosis, acidosis, diabetic precoma and coma.
Side Effects
The drug has certain side effects, that can affect individuals in different
ways. The following are some of the side effects, that are often associated
with the drug:
- Cutaneous reactions
- Blood dyscrasias
Disclaimer: The above information is for general understanding
of the visitor. Please consult a registered medical practitioner before
taking the aforesaid medicine.
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