Gliclazide is an
anti-diabetic agent with both metabolic and vascular properties. It
restores the early peak of insulin secretion and ensures glycaemic
control throughout 24 hours without hypoglycaemia.
The drug combats microthrombosis by decreasing platelet hyper
adhesiveness & hyper aggregation, increasing fibrinolytic
activity, normalizing prostaglandin metabolism, scavenging
free-radicals.
The drug is also used in combination with a strict diet and
exercising regime for controlling high blood sugar in non-insulin
dependent diabetic patients.
Brand Name: Amaryl, DiaBeta, Diabinese, Dymelor, Glucotrol,
Glucotrol XL
Chemical Description
Dosage
80-320 mg daily. Usually160 mg daily.
Contra- Indications: Pregnancy, Severe renal or hepatic
failure, severe ketosis, acidosis, diabetic precoma and coma.
Side Effects
The drug has certain side effects, that can affect individuals in
different ways. The following are some of the side effects, that are
often associated with the drug:
- Cutaneous reactions
- Blood dyscrasias
Disclaimer: The above information is for general
understanding of the visitor. Please consult a registered medical
practitioner before taking the aforesaid medicine.