Domperidone is an antidopaminergic drug,
that can either be used orally or intravenously, for suppressing nausea and
vomiting. The drug has also been used for stimulating lactation.
Domperidone is a potent dopamine antagonist with antiemetic properties. It
is useful in treatment of nausea, vomiting and dyspepsia. It increases lower
oesophagal sphincter pressure, antral and duodenal contractions, gastric
emptying of liquids and semi solids, and shortens the stationary phase for
solids in the stomach.
Brand Name: Motillium
Iupac Name:
1,3-dihydro-5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-2H-benzimidazol-2-one
Dosage
Adults: 20-40 mg , 3-4 times a day. In elderly commence at 10 mg
Children: 0.3 mg/ kg body weight, 3-4 times daily before meals and
at bed time.
Contra- Indications: Pregnancy
Side Effects
The drug has certain side effects, that can affect individuals in different
ways. The following are some of the side effects, that are often associated
with the drug:
- Serum prolactin level may increase resulting in galactorrhoea in
females & less frequently gynaecomastia in males.
Disclaimer: The above information is for general understanding
of the visitor. Please consult a registered medical practitioner before
taking the aforesaid medicine.
Injection
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