Generic name:
Cyclophosphamide Injection
Brand name: Cytoxan, Neosar
Description
Cyclophosphamide is also known as cytophosphane. This belongs to
the group of medicines called the oxazophorines group. It is a
nitrogen mustard alkylating agent, which interferes with the growth
of cancer cells and slows their growth in the body. It is a "prodrug"
which is transformed to some active forms that have chemotherapeutic
activity in the liver, which treats various types of cancer and some
autoimmune disorders.
Uses
- Cyclophosphamide is used with other chemotherapy agents to
treat lymphomas, some forms of leukemia.
- It is used to treat some solid tumors.
- It is also used to treat certain cases of nephrotic syndrome
such as kidney disease in children.
- Cyclophosphamide is also used to treat Minimal Change
Disease and rheumatoid arthritis.
- It is still used for Wegener's granulomatosis, under the
brand name Endoxan.
Safety tips
- Before taking cyclophosphamide, tell your doctor if you
- have an infection
- have a low level of white blood cells
- have had recent vaccinations
- have bone marrow problems
- have been earlier treated with x-ray therapy or other
chemotherapy medicines
- need to have surgery
- have any unhealed wounds
- have had your adrenal glands removed
- have heart, liver or kidney disease
- Do not take this medication if you are pregnant or breast
feeding.
Side effects
Some side effects are common while taking anti cancer medicines for
which no medical attention is required such as hair loss, difficulty
breathing, tiredness, mouth ulcers, numbness etc. However, you
should immediately consult your doctor if you have the following
serious side effects:
- An allergic reaction
- Blood in the urine or Difficult urination
- Black stools
- Signs of infection like fever, chills
- Jaundice
- Chest pain
- Unusual bleeding
- Changes in bone marrow function etc.
Disclaimer: The above information is for general
understanding of the visitor. Please consult a registered medical
practitioner before taking the aforesaid medicine.
