Cefuroxime is an antibiotic resistant
to most betalactamases and is active against a wide range of Gram-positive
and Gram -negative organisms. The most important use of the drug is in
treating meningitis caused by H. influenzae, meningcocci an pneumococcoi.
This is so, because it attains high concentrations in C.S.F.
Brand Name: Zinnat
Chemical Description: 4-(carbamoyloxymethyl)-8-
[2-(2-furyl)-2-methoxyimino-acetyl]amino -7-oxo-
2-thia-6-azabicyclo[4.2.0]oct -4-ene-5-carboxylic acid
Dosage
Adults: 750 mg thrice daily i.m or i.v. Severe infections: 1.5 gm
daily i.v. Total dose 3-6 gram daily
Children and infants: 30-100 mg/kg body weight daily in 3-4 divided
doses.
Neonates: 100mg/kg body weight i.v. daily
This cephalosporin antibiotic can be administered orally and parenterally
for treating respiratory, skin, and other infections.
Contra Indications: Patients with known hypersensitivity to
cephalosporin antibiotics
Side Effects
The drug has certain side effects, that can affect individuals in different
ways. The following are some of the side effects, that are often associated
with the drug:
- Skin Rashes
- Eosinophilia
- Transient increase of hepatic enzymes
Pregnant and lactating mothers should use the drug with caution and
after consulting a medical practitioner.
Disclaimer: The above information is for general understanding
of the visitor. Please consult a registered medical practitioner before
taking the aforesaid medicine.