Ceftriaxone is an antibiotic
belonging to the class of drugs called cephalosporins. It is a prescription
drug. Ceftriaxone is available in injection form and can be administered
either intravenously (into a vein) or intramuscularly (into a muscle). It is
available as a powder for solution. Ceftriaxone is used to treat bacterial
infections in many different parts of the body. This drug is also given
before certain types of surgery to prevent infections.
Brand Name of Ceftriaxone Injection
Rocephin
Ceftriaxone Injection
Chemical description
(6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-ylthio)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic
acid
Use of Ceftriaxone Injection
Ceftriaxone Injection is used for
fighting bacteria in the body. It treats different types of bacterial
infections including Bronchitis, pneumonia, bone infections, abdominal and
skin infections, urinary tract infections etc.
Dosage of Ceftriaxone Injection
Depending on the disease, the
patient is given different doses such as follows:
Meningitis:
Adults: 4gm i.v. Initially followed by 2gm i.v. Once daily for ten
days or 72 hours after fever abates.
Children: 75-100mg/kg body weight for 7-9 days
Typhoid:
Adults: 4 gm daily for 2 days followed by 2 gm daily for 2 days.
Children: 75 mg/kg body weight daily for 7 days.
Other Conditions:
Adults: 1-2 grams daily
Children: 50-75 mg/kg body weight daily
Contra- Indications of Ceftriaxone Injection
Hypersensitivity. Do
not mix ceftriaxone with any diluent that contains calcium, including a
total parenteral nutrition (TPN) solution.
Side Effects of Ceftriaxone Injection
The drug has certain side
effects, that can affect individuals in different ways. The following are
some of the side effects, that are often associated with the drug:
- Diarrhoea
- Nausea or vomiting
- Blood or mucous in stool
- Allergic reaction like rash
Pregnant and lactating women should use the drug with caution. Dose
should be decreased in elderly people in case of renal impairment.
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Disclaimer: The above information is for general understanding
of the visitor. Please consult a registered medical practitioner before
taking the aforesaid medicine.