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Ceftriaxone Injection


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Ceftriaxone is an antibiotic belonging to the class of drugs called cephalosporins. It is a prescription drug. Ceftriaxone is available in injection form and can be administered either intravenously (into a vein) or intramuscularly (into a muscle). It is available as a powder for solution. Ceftriaxone is used to treat bacterial infections in many different parts of the body. This drug is also given before certain types of surgery to prevent infections.

Brand Name of Ceftriaxone Injection

Rocephin
Ceftriaxone Injection

Chemical description

(6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-ylthio)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Use of Ceftriaxone Injection

Ceftriaxone Injection is used for fighting bacteria in the body. It treats different types of bacterial infections including Bronchitis, pneumonia, bone infections, abdominal and skin infections, urinary tract infections etc.

Dosage of Ceftriaxone Injection

Depending on the disease, the patient is given different doses such as follows:
Meningitis:
Adults: 4gm i.v. Initially followed by 2gm i.v. Once daily for ten days or 72 hours after fever abates.
Children: 75-100mg/kg body weight for 7-9 days

Typhoid:
Adults: 4 gm daily for 2 days followed by 2 gm daily for 2 days.
Children: 75 mg/kg body weight daily for 7 days.

Other Conditions:
Adults: 1-2 grams daily
Children: 50-75 mg/kg body weight daily

Contra- Indications of Ceftriaxone Injection

Hypersensitivity. Do not mix ceftriaxone with any diluent that contains calcium, including a total parenteral nutrition (TPN) solution.

Side Effects of Ceftriaxone Injection

The drug has certain side effects, that can affect individuals in different ways. The following are some of the side effects, that are often associated with the drug:
  • Diarrhoea
  • Nausea or vomiting
  • Blood or mucous in stool
  • Allergic reaction like rash
Pregnant and lactating women should use the drug with caution. Dose should be decreased in elderly people in case of renal impairment.

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Disclaimer: The above information is for general understanding of the visitor. Please consult a registered medical practitioner before taking the aforesaid medicine.

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