Ceftriaxone is an antibiotic
belonging to the class of drugs called cephalosporins. It is used
for fighting bacteria in the body. It treats different types of
bacterial infections including Bronchitis, pneumonia, bone
infections, abdominal and skin infections, urinary tract infections
etc.
Ceftriaxone is available in injection form and can be administered
either intravenously (into a vein) or intramuscularly (into a
muscle).
Brand Name: Rocephin
Chemical description:
(6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-ylthio)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic
acid
Dosage
Meningitis:
Adults: 4gm i.v. Initially followed by 2gm i.v. Once daily
for ten days or 72 hours after fever abates.
Children: 75-100mg/kg body weight for 7-9 days
Typhoid:
Adults: 4 gm daily for 2 days followed by 2 gm daily for 2
days.
Children: 75 mg/kg body weight daily for 7 days.
Other Conditions:
Adults: 1-2 grams daily
Children: 50-75 mg/kg body weight daily
Contra- Indications: Hypersensitivity
Side Effects
The drug has certain side effects, that can affect individuals in
different ways. The following are some of the side effects, that are
often associated with the drug:
- Diarrhoea
- Nausea or vomiting
- Blood or mucous in stool
- Allergic reaction like rash
Pregnant and lactating women should use the drug with caution.
Dose should be decreased in elderly people in case of renal
impairment.
Disclaimer: The above information is for general
understanding of the visitor. Please consult a registered medical
practitioner before taking the aforesaid medicine.
