Azithromycin is one of the world's
best selling antibiotics. It is an azalide antibiotic, a subclass of the
macrolides. It retains the spectrum of activity of erythromycin against
Gram-positive and Gram-negative pathogens and has increased activity against
many Gram - negative and atypical microorganisms.
The antibiotic is commonly used for treating certain bacterial infections,
most often bacteria causing middle ear infections, tonsillitis, throat
infections, bronchitis, pneumonia, sinusitis and laryngitis,
Brand Name: Zithromax, Zmax®; Sumamed®; Aztrin®
Chemical Description: 9-deoxy-9a-aza-9a-methyl-9a- homoerythromycin
A
Working
The drug acts by interfering with microbial protein synthesis by binding to
the 50 S ribosomal sub unit. The antibiotic has been approved for treating
chlamydia and bacterial infections of the skin and respiratory tract.
The drug is commonly administered in tablet or oral suspension form. It is
also available for intravenous injection. The Tablets are available in 250mg
and 500mg doses; Oral suspension comes in strength of 100mg/teaspoon and
200mg/teaspoon
Dosage
Upper and lower respiratory tract and skin and soft tissue infections:
500mg once daily for 3 days or 500 mg once on day 1, followed by 250 mg once
daily for the next 4 days. Urogenital infection (Chlamydial) : 1g as a
single dose
The drug should be taken 1 hour before or at least 2 hours after a meal. It
used with caution by pregnant and lactating women.
Contra- Indications: Hypersensitivity to azithromycin or other
macrolides
Side Effects
The drug has certain side effects, that can affect individuals in different
ways. The following are some of the side effects, that are often associated
with the drug:
- Nausea
- Vomiting
- Abdominal pain
- Dyspepsia
- Flatulence Dizziness
- Vertigo
- Headache
Disclaimer: The above information is for general understanding
of the visitor. Please consult a registered medical practitioner before
taking the aforesaid medicine.
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