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Pharmaceutical Drugs

Glossary



ANTIBIOTICS


Antibiotics are medicines that kill the bacteria that cause infections.

Purpose
Physicians and patients have come to depend on antibiotics to treat everything from sore throats and urinary tract infections to Meningitis and Tuberculosis. These drugs are also used to prevent infections before, during, and after surgery. But in recent years, health experts have noticed that antibiotics are becoming less and less effective as people use them more and more. This happens because of antibiotic resistance, a problem that develops when antibiotics are over-used or mis-used.

Everyone can help keep antibiotic resistance from becoming an even bigger problem than it already is. Here are some important guidelines:
  • Do not pressure a physician to prescribe an antibiotic for a cold or flu. Usually, such illnesses are due to a viral infection, which cannot be treated with an antibiotic. Taking an antibiotic when it is not needed will only encourage the spread of resistant bacteria in the body and in the community.
  • If a physician prescribes an antibiotic, do not be afraid to ask why the medicine is being prescribed. Make sure the physician has good reason to believe that the medicine will effectively treat the particular condition for which it is being prescribed.
  • When an antibiotic is appropriately prescribed, be sure to take all the medicine, for as long as directed. When a patient stops taking the medicine too soon, only the most vulnerable bacteria are killed, leaving the rest to thrive. Any illness caused by the remaining, resistant bacteria will then be harder to treat.

    Description
    Different antibiotics kill bacteria in different ways. Some short-circuit the processes by which bacteria get energy, others disturb the structure of the bacterial cell wall, and still others interfere with the production of essential proteins.

    Some 150 antibiotics are available. These include Tetracyclines, Aminoglycosides, Penicillins, Cephalosporins, Fluoroquinolones, Streptogramins, Sulfonamides, and Erythromycins.

    Antibiotics are classified as narrow-spectrum drugs when they work against only a few types of bacteria. Broad-spectrum antibiotics are effective against a wide range of bacteria. However, broad-spectrum antibiotics are more likely to promote antibiotic resistance. For that reason, narrow-spectrum antibiotics, which often cost less, should be used whenever possible. Broad-spectrum antibiotics should be reserved for infections that do not respond to treatment with narrow-spectrum drugs.