Anti-Parkinson Drugs are medicines that relieve the symptoms of Parkinson's
disease and other forms of Parkinsonism. All Anti- Parkinson Drugs are
available only with a physician's prescription. They are sold in tablet
(regular and extended-release), liquid, extended-release capsule, and
injectable forms.
What is Parkinson's Disease?
Parkinson's disease is the most common
form of Parkinsonism. It is a disorder of the brain. All types of
Parkinsonism occur when nerve cells in a particular part of the brain die or
lose the ability to function. These cells normally produce a chemical called
Dopamine, a chemical messenger that helps relay signals to different parts
of the brain. This process is important in producing smooth, coordinated
movement throughout the body. When Dopamine-producing cells are lost, normal
movement becomes impossible. In people with late-stage Parkinson's disease,
80% or more of these important cells are dead or impaired.
Symptoms of Parkinson's Disease?
- Tremor or trembling in the hands, arms, legs, jaw, and face
- Stiffness or rigidity of the arms, legs, and trunk.
- Slowness of movement (Bradykinesia)
- Poor balance and coordination
- Automatic movements (such as blinking) slow or stop.
- Lack of expression in the face etc.
Treatmet Using Antiparkinson Drugs
It is to be noted that there is
no cure for Parkinson's disease or other forms of Parkinsonism exists, but
several drugs help relieve the symptoms. Some drugs replenish Dopamine in
the brain. Others mimic the role of Dopamine or block the effects of other
chemicals that cause problems in the brain when Dopamine levels drop.The
goal of treatment is to control symptoms. Inspite of continued medications,
there are cases of the symptoms recurring when the helpful effects of the
medication wears off. In such cases, the doctor needs to change the type of
medication, the dose, time gap between doses. The treatment program needs to
properly inspected for further changes. Never change or stop taking any
medications without talking with your doctor.
Popular Anti Parkinson Drugs
- Levodopa (L-dopa), Sinemet, levodopa and carbidopa (Atamet)
- Pramipexole (Mirapex), ropinirole (Requip), bromocriptine (Parlodel)
- Selegiline (Eldepryl, Deprenyl), rasagiline (Azilect)
- Amantadine or anticholinergic medications. They reduce early or mild
tremors
- Entacapone. This prevents the breakdown of levodopa.
- Levodopa, which is used alone or in combination with
Carbidopa, restores Dopamine levels in the brain. Carbidopa helps make
Levodopa more effective and reduces some of the side effects that occur
when Levodopa is taken by itself. Anti-Dyskinetics and Anti-Cholinergics
block the effects of other brain chemicals, thereby reducing some of the
involuntary tremors.
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