Anti-Hypertensive Drugs are medicines that are used to help lower blood
pressure or reduce hypertension.
High Blood Pressure and Hypertension
Anti-Hypertensive Drugs are
used to help control blood pressure in people whose blood pressure is too
high. Some people have blood pressure that stays high all the time. This
condition is known as hypertension. Being aware of high blood pressure and
doing something to control it are very. Untreated, high blood pressure can
lead to diseases of the heart, arteries, kidney damage, or stroke.
For high blood pressure treatment, the type of hypertension needs to be
known. In most cases the common cause of high blood pressure is Essential or
Primary Hypertension, which means that the high blood pressure is not caused
by some other medical condition. Such high pressure problems can be
controlled by anti hypertension medication and changes in diet, doing
regular exercise, and controlling weight. Controlling primary hypertension
is a life long treatment.
The other type of hypertension is secondary hypertension. This is caused
due to medical problems like kidney disease, narrowing of certain arteries,
or adrenal glands tumors. Correcting these problems often cures the problem
of high blood pressure, and no further treatment is needed.
How Does Hypertension Medication Works?
Hypertension medication
works in the following ways:
- They reduce blood volume. This in turn reduces central venous
pressure and cardiac output).
- They reduce systemic vascular resistance.
- They reduce cardiac output by depressing heart rate and stroke
volume.
Drugs Used to Treat Hypertension/High Blood Pressure
Many different
types of drugs are used, alone or in combination with other drugs, to treat
hypertension/high blood pressure. The major categories are: ·
- Angiotensin-converting Enzyme (ACE) Inhibitors: They work by
preventing a chemical in the blood, angiotensin I, from being converted
into a substance that increases water and salt retention in the body.
They make blood vessels relax, which further reduces blood pressure. ·
- Angiotensin II Receptor Antagonists: They act at a later step in the
same process that ACE inhibitors affect. Like ACE inhibitors, they lower
blood pressure by relaxing blood vessels. ·
- Beta blockers: Beta blockers affect the body's response to certain
nerve impulses. This, in turn, decreases the force and rate of the
heart's contractions, which lowers blood pressure. ·
- Blood Vessel Dilators (Vasodilators): These drugs lower blood
pressure by relaxing muscles in the blood vessel walls. ·
- Calcium Channel Blockers: They slow the movement of calcium into the
cells of blood vessels. This relaxes the blood vessels and lowers blood
pressure. ·
- Diuretics: They control blood pressure by eliminating excess salt and
water from the body. ·
- Nerve Blockers: They control nerve impulses along certain nerve
pathways. This allows blood vessels to relax and lowers blood pressure.
Popular Hypertension Drugs
- Propranolol (Inderal)
- Atenolol (Tenormin)
- Pindolol (Visken)
- Losartan (Cozaar)
- Candesartan (Atacand)
- lirbesartan (Avapro)
- Telmisartan (Micardis)
- Valsartan (Diovan)
- Eprosartan (Teveten) etc.