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Finished Formulations
Pharmaceutical Drugs

Glossary



AMPICILLIN


Ampicillin is an antibiotic belonging to the class of drugs called penicillins. It is one of the most widely prescribed antibiotics and fights bacteria in human body. The drug is used to treat many types of infections, including tonsillitis, pneumonia, bronchitis, urinary tract infections, gonorrhea, and infections of the intestines or food poisoning.

Brand Name: Omnipen; Polycillin; Principen

Chemical Description: 7-(2-amino-2-phenyl-acetyl)amino-3,3-dimethyl-6-oxo-2-thia-5-azabicyclo[3.2.0]heptane-4-carboxylic acid

Working
Ampicillin belongs to the group of beta-lactam antibiotics, and is able to penetrate Gram-positive bacteria. The drug inhibits the third and final stage of bacterial cell wall synthesis, which ultimately leads to cell lysis.

Ampicillin is available in tablet, capsules and liquid forms. The amount of drug should be taken as per the doctor's prescription. The drug should be taken at evenly spaced intervals. The capsules/ tablets/liquid are available in varying potencies of 250mg and 500 mg depending on the severity of the individual case.

Dosage
Adults: 250-500mg 8 hourly or as required
Children:125-250 mg 6 hourly or according to age
Infants: 50- 150 mg/kg body weight in 2-4 divided doses

Contra- Indications: Hypersensitivity to penicillin

Side Effects
The drug has certain side effects, that can affect individuals in different ways. The following are some of the side effects, that are often associated with the drug:
  • Skin rash
  • Pruritus
Simultaneous use of the drug with oral contraceptives may lead to break through bleeding or pregnancy. The drug is safe for usage by pregnant, lactating women and elderly.

Disclaimer: The above information is for general understanding of the visitor. Please consult a registered medical practitioner before taking the aforesaid medicine.