Amoxycillin is a
semi-synthetic penicillin, an analogue of ampicillin, with a broad
range of bactericidal activity against many gram-positive and
gram-negative micro-organisms. It is stable in presence of gastric
acid and may be given without regard to meals. It acts through
inhibition of biosynthesis of cell wall mucopeptide.
Amoxycillin is considered a good choice for treating acute
sinusitis, acute otitis media, and of acute exacerbations of chronic
bronchitis. The drug is superior to ordinary penicillin in these
cases.
Brand Name: Amoxil, Penamox, Moxlin
Iupac Name: 7-[2-amino-2-(4-hydroxyphenyl)
-acetyl]amino-3,3-dimethyl-6-oxo 2-thia-5-azabicyclo[3.2.0]heptane
-4-carboxylic acid
Working
The drug works by inhibiting bacterial cell walls synthesis. It
also slows down or inhibits cross-linkage between the linear
peptidoglycan polymer chains that constitute a major component of
the cell wall of Gram-positive bacteria.
The drug, in its trihydrate form is available as tablets, capsules,
or syrup for oral use, and as sodium salt for being intravenously
administration
Dosage
Adult: 250mg to 1 gm thrice daily
Children : 20 mg/kg body weight in 3 divided doses
Contra- Indications
Individuals with a history of an allergic reaction to penicillin.
Pregnancy
Side Effects
The drug has certain side effects, that can affect individuals in
different ways. The following are some of the side effects, that are
often associated with the drug:
- Nausea
- Vomiting
- Diarrhoea
- Skin rashes
There is no known problem with use by elderly people. It can be
safely used by lactating mothers.
Disclaimer: The above information is for general
understanding of the visitor. Please consult a registered medical
practitioner before taking the aforesaid medicine.
