Amlodipine besylate is an orally
administered drug, used for treating hypertension and angina pectoris. It
has a long duration action for treating them. This calcium channel blocker
is available in tablet form. The tablets are available in varying potencies
of 5mg and 10 mg depending on the severity of the individual case.
Brand Name: Norvasc
Chemical Description: 3-Ethyl-5-methyl (±)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate,
mono-benzenesulphonate.
Working
The drug inhibits the trans membrane influx of calcium ions into the
cardiac muscle and smooth muscle. It is very useful for treating chronic,
stable and vasospastic angina. The drug works by blocking the calcium needed
for muscle contraction and works primarily on the arterial muscle. The
effect of this drug is to relax the arterial muscles, leading to their
dilation and finally a drop in the blood pressure within them.
Dosage: 5 to 10 mg once a day
Contra- Indications: Hypersensitivity
Side Effects
The drug has certain side effects, that can affect individuals in different
ways. The following are some of the side effects, that are often associated
with the drug:
- Headache
- Fatigue
- Dizziness
- Flushing
- Palpitation
- Nausea
The drug should not be given to pregnant and lactating women, the
dosage of the drug should be reduced when given to elderly. The side effects
of the drug mentioned above may or may not occur in individuals.
Disclaimer: The above information is for general understanding
of the visitor. Please consult a registered medical practitioner before
taking the aforesaid medicine.
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