Amlodipine besylate is an orally administered drug, used for treating
hypertension and angina pectoris. It has a long duration action for treating
them. This calcium channel blocker is available in tablet form. The tablets
are available in varying potencies of 5mg and 10 mg depending on the
severity of the individual case. It is a
prescription drug
and is not available over the counter.
Brand Names of Amlodipine Besylate
Azor (combination), Exforge
(combination), Caduet, Lotrel, Norvasc
Chemical Description
3-Ethyl-5-methyl (±)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate,
mono-benzenesulphonate.
Uses of Amlodipine Besylate
Amlodipine Besylateis used in the
treatment of hypertension, and coronary artery disease. The drug is used
alone or in combination with other classes of antihypertensive agents. It
can be used in fixed combination with olmesartan, benazepril, or valsartan
when such combined therapy is indicated.
Working of Amlodipine Besylate
The drug inhibits the trans membrane
influx of calcium ions into the cardiac muscle and smooth muscle. It is very
useful for treating chronic, stable and vasospastic angina. The drug works
by blocking the calcium needed for muscle contraction and works primarily on
the arterial muscle. The effect of this drug is to relax the arterial
muscles, leading to their dilation and finally a drop in the blood pressure
within them.
Dosage:
5 to 10 mg once a day
Side Effects of Amlodipine Besylate
The drug has certain side
effects, that can affect individuals in different ways. The following are
some of the side effects, that are often associated with the drug:
- Headache
- Fatigue
- Dizziness
- Flushing
- Palpitation
- Nausea
The drug should not be given to pregnant and lactating women, the
dosage of the drug should be reduced when given to elderly. The side effects
of the drug mentioned above may or may not occur in individuals.
Disclaimer: The above information is for general understanding
of the visitor. Please consult a registered medical practitioner before
taking the aforesaid medicine.