Alfacalcidol is a commonly used drug
for treating vitamin D deficiency. It is derived from Vitamin D and is used
by the body for regulation of Calcium and Phosphate. It helps to increase
the vitamin D absorption in the body.
Brand Name: Alfa D, One-Alfa, Calcijex, Calciferol
Working
The drug is a form of Vitamin D and gets converted rapidly in the liver
into calcitrol. Alfacalcidol is used for controlling the intestinal
absorption of calcium and phosphate and plays a significant role in
regulating the bone mineralization.
In cases of chronic renal failure, oral administration of this drug helps
to increase the production of calcitrol and remove abnormalities of calcium
and phosphate. In turn, this results in curing intestinal malabsorption of
calcium and phosphate and also increased blood calcium levels.
Alfacalcidol is also given for a more rapid increase in active vitamin D
and hence calcium, in people suffering from bone diseases. This form of
Vitamin D is more effective and provides a quicker response than the normal
dietary vitamin D supplements.
Used For
Alfacalcidol is very useful for treating:
- Hypocalcaemia or low blood calcium levels in the neonate.
- Hypoparathyroidism or Low parathyroid function or
- Hyperparathyroidism or Over activity of the parathyroid glands
- Softening of the bones due to lack of Vitamin D in the body
- Correction of calcium and phosphate metabolism abnormalities in renal
osteodystrophy.
Dosage
Adults: 1mcg/day, Lederly: 0.5mcg/day
Children under 20 kg: 0.05 mcg/day
Premature infants and neonates:
Contra-indications: Hypercalcaemia, hyperphosphataemia without
hypoparathyroidism and hyper- magnesaemia
Side Effects
The drug has certain side effects, that can affect individuals in different
ways. The following are some of the side effects, that are often associated
with the drug:
- Central Nervous System Depression
- Nausea
- Vomiting
- Thirst
- Constipation
- Drowsiness
There are no known side effects of this drug, when used by pregnant
women.
Disclaimer: The above information is for general understanding
of the visitor. Please consult a registered medical practitioner before
taking the aforesaid medicine.
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