Alfacalcidol is a commonly
used drug for treating vitamin D deficiency. It is derived from
Vitamin D and is used by the body for regulation of Calcium and
Phosphate. It helps to increase the vitamin D absorption in the
body.
Brand Name: Alfa D, One-Alfa, Calcijex, Calciferol
Working
The drug is a form of Vitamin D and gets converted rapidly in the
liver into calcitrol. Alfacalcidol is used for controlling the
intestinal absorption of calcium and phosphate and plays a
significant role in regulating the bone mineralization.
In cases of chronic renal failure, oral administration of this drug
helps to increase the production of calcitrol and remove
abnormalities of calcium and phosphate. In turn, this results in
curing intestinal malabsorption of calcium and phosphate and also
increased blood calcium levels.
Alfacalcidol is also given for a more rapid increase in active
vitamin D and hence calcium, in people suffering from bone diseases.
This form of Vitamin D is more effective and provides a quicker
response than the normal dietary vitamin D supplements.
Used For
Alfacalcidol is very useful for treating:
- Hypocalcaemia or low blood calcium levels in the neonate.
- Hypoparathyroidism or Low parathyroid function or
- Hyperparathyroidism or Over activity of the parathyroid
glands
- Softening of the bones due to lack of Vitamin D in the body
- Correction of calcium and phosphate metabolism abnormalities
in renal osteodystrophy.
Dosage
Adults: 1mcg/day, Lederly: 0.5mcg/day
Children under 20 kg: 0.05 mcg/day
Premature infants and neonates:
Contra-indications: Hypercalcaemia, hyperphosphataemia
without hypoparathyroidism and hyper- magnesaemia
Side Effects
The drug has certain side effects, that can affect individuals in
different ways. The following are some of the side effects, that are
often associated with the drug:
- Central Nervous System Depression
- Nausea
- Vomiting
- Thirst
- Constipation
- Drowsiness
There are no known side effects of this drug, when used by
pregnant women.
Disclaimer: The above information is for general
understanding of the visitor. Please consult a registered medical
practitioner before taking the aforesaid medicine.
