9 Feb 2011 Avandia is an anti-diabetic drug for type 2 diabetic patients. The generic name of this drug is Rosiglitazone, belonging to the thiazolidinedione class of drugs. This drug works as an insulin sensitizer. Rosiglitazone is produced by GlaxoSmithKline (GSK) and marketed in the name of Avandia as a stand alone drug.
Avanndia was a very popular drug till a few years back. Infact GSK achieved an annual peak sales of approximately $2.5bn in 2006. Over 6 million people worldwide have been using Avandia since its production. However this drug has slowly lost its popularity after reports of severe side effects of the drugs. In many countries , the drug has already been banned. A safety alert was issued in 2007 by the FDA. The drug is still in use in USA as as per law, the drug's patent expires in 2012.
Some of the mild Avandia side effects include headache, back pain, fatigue, and sinusitis, among others. However the drug has been linked to other severe side effects like
Of all the side effects, risk to the heart has been the one of the main factor of this Type 2 diabetes drug that has been the major concern, and the most controversy.
Avandia lawsuits have resulted because of the serious Avandia side effects, including congestive heart failure, hepatitis, and liver failure. While thousands of lawsuits brought against GSK have already been settled, including lawsuits for Avandia death, there were more lawsuits produced as a result of the announcement of more severe restrictions by the FDA in September, 2010.